Gospel photoimmunotherapy promotes wound healing and regeneration in patients with chronic lower extremity ulcers

      Reporter Zhong Peifang/Taipei Report] Two patients at National Taiwan University suffered from venous ulcerative wounds. The 71-year-old and 75-year-old grandmothers treated the skin wound with light three times, and the wound changed from 3×1.5cm to 2×1.5. Stimulates wound cells and proliferates cells.

    Cai Chengfang, Department of Dermatology, National Taiwan University Hospital, said that phototherapy is a new gospel for patients with chronic lower extremity ulcers, promoting wound healing and regeneration. Phototherapy is traditionally based on photoimmunotherapy, while photoregenerative medicine is the latest development. Especially in an aging society, the rate of chronic lower extremity ulcers caused by diabetes and arteriovenous circulation disorders is increasing year by year, and one of the major applications of photoregenerative medicine is to promote wound healing. The integrated phototherapy center of our hospital uses low-energy laser, infrared linear polarized light irradiator, light-emitting diode therapy device (to be introduced), stimulates cell regeneration with the principle of photobiostimulation, improves skin microcirculation, and is used for traditional therapy treatment. In the case of ineffective chronic venous stagnation type ulcer, after one to three treatments once a week, the ulcer wound area can be reduced to 50% of the original, and there is a significant pain relief effect.

    The first non-invasive skin microcirculation examination method (microvascular Doppler imaging scan) is used to detect microvascular blood flow and oxygen flow, instantly assess the blood oxygen flow of skin tissue, and accurately evaluate the efficacy and prognosis of ulcer wounds. After the ulcer was treated with light, the blood flow and oxygen volume of the wound were significantly improved. The best loops will appear red in the imaging scan, and the fingers of diabetic patients will appear black when the scan is not used. Doppler microcirculation examination, with 44 degrees C heat stimulation response, healthy people will increase by more than 6 times, while diabetic patients will only increase by 2 to 3 times.

The first low-energy laser treatment of leukoplakia without side effects uses visible light to regenerate and protect melanocytes to treat refractory leukoplakia, and its curative effect is about 70%. Compared with other treatments, there are few side effects, and the skin color is very natural when vitiligo is restored.

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